Study sheds light on Schwann cell adaptation in tissue repair

Study sheds light on Schwann cell adaptation in tissue repair

 

Thursday, 5 October, 2017

Professor Timothy Aitman (Centre for Genomics & Experimental Medicine) has published a study in Cell Reports that identifies the epigenetic mechanisms involved in the generation of repair Schwann cells after nerve injury.

Schwann cells play an important role in the repair of injured peripheral nerves. Following injury these cells change and generate a distinct cell type - the repair Schwann cell - which is involved in maintenance, regeneration and repair of the nerve cell. In this large scale study they provide more detailed understanding of the molecular and genetic changes that occur in these cells after nerve injury.

Prof Timothy Aitman,  who co-led the study, said: “Our findings give us insight into how cells in the body adapts to injury.This knowledge will help identify drug targets for much-needed therapies to help patients with peripheral neuropathy and traumatic nerve injuries.