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Dr Emily Osterweil and researchers at the Patrick Wild Centre for Research into Autism, Fragile X Syndrome and Intellectual Disability have used a genetic mouse model of Fragile X Syndrome, an inherited form of autism, to look at the changes in muscarinic M4 receptor pathway. They found that a paradoxical enhancement of M4 activity normalised activity and reduced seizures in these mice.
On Wednesday 28 June 2017, members of the University of Edinburgh's Stroke Research Group (SRG), both past and present, gathered to celebrate 30 years of stroke research in Edinburgh. There was an excellent turn out for the celebration, including Professor Emeritus Charles Warlow, and Peter Sandercock presented a nostalgic walk down memory lane before cutting the cake.
Professors Joanna Wardlaw (Centre for Clinical Brain Sciences, University of Edinburgh), Karen Horsburgh (Centre for Neuroregeneration, University of Edinburgh) and Rhian Touyz (Institute of Cardiovascular & Medical Sciences, University of Glasgow) are guest editors on the recently released Clinical Science special edition on small vessels, dementia & chronic disease.
Congratulations to Prof Seth Grant (Centre for Clinical Brain Sciences) and his research group, who have been awarded a grant of £1.3m by the Wellcome Trust to map the human brain. The project is built upon their previous work creating another such map - called a synaptome - for the mouse brain. The researchers hope to map the trillions of connections between brain cells, potentially revealing new insights into the foundations of behaviour and brain disease.
Congratulations to Dr Emily Sena, CAMARADES group, Centre for Clinical Brain Sciences on being appointed first Editor-in-Chief at BMJ Open Data. This new journal is dedicated to applying open science principles to preclinical and basic research, with open access, open peer review, and has an open data policy.
The University of Edinburgh is joining with five other institutions to form the UK Dementia Research Intitute (UK DRI), along with charity partners Alzheimer's Society and Alzheimer's Research UK.
Watch Edinburgh Imaging's new video to find out more about their scanners and imaging services at
Professor Neil Mabbott (The Rosin Institute) and colleagues have discovered why some people appear more susceptible to infection by prion proteins, which cause variant Creutzfeldt-Jakob disease (vCJD) in people and bovine spongiform encephalopathy (BSE) in cows.
Dr Barry McColl (Roslin Institute, University of Edinburgh) and colleagues have found that following a stroke patients have reduced levels of protective antibodies in their blood.
Dr Christos Gkogkas and colleagues (Centre for Discovery Brain Sciences, and Patrick Wild Centre) have published a study that may shed light on why a certain category of antidepressant drugs stop working in some people.