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The Centre for Clinical Brain Sciences (CCBS) was profiled in The Lancet, in an article outlining the structure and research focus of the Centre.
Scientists led by Dr Tilo Kunath (MRC Centre for Regenerative Medicine) have taken a key step towards improving an emerging class of treatments for Parkinson’s disease. The advance could improve a next generation of therapies for the condition, which affects around one in 350 people in the UK.
Three collaborative pilot project grants have been awarded to foster trans-Atlantic cooperation
Professor Sir Ian Wilmut (The Roslin Institute), lead scientist in the project that created Dolly the Sheep, has announced, on World Parkinson's Disease Day, that he is backing a major new Parkinsons's disease research programme between Dundee and Edinburgh after being diagnosed with the condition.
A team of researchers at the University of Edinburgh's Medical Research Council Centre for Regenerative Medicine (MRC CRM) have made a key discovery that could speed up the production of cells in the lab for studying diseases such as multiple sclerosis and Parkinson’s disease. It is possible that it could also help to boost supplies of cells for use in drug discovery research and could eventually aid production of cells for use as therapies.
Dr David Hay, Dr Baltasar Lucendo-Villarin, Jose Meseguer-Ripolles and Dr Kate Cameron (all MRC Centre for Regenerative Medicine, University of Edinburgh), in collaboration with the Universities of Aberdeen and Glasgow, have developed a stem cell technique to assess the effects of maternal cigarette smoking on the developing foetus. Their findings reveal that the potent cocktail of chemicals in cigarettes is particularly harmful to developing liver cells and affects male and female foetuses differently.
People with sight problems could benefit from a surgical trial advance that has been shown to help restore the surface of the eye. Doctors led by Professor Baljean Dhillon (Centre for Clinical Brain Sciences) made the world-first step by carrying out a clinical trial using stem cells from donors to create tissue that was transplanted into patients with a condition that causes blindness. Researchers say the trial offers clues about how eye tissue loss could be repaired using stem cells from organ donors. It also sheds light on the causes of sight disorders. The trial focused on limbal stem cell deficiency (LSCD), which can result from damage to eye from chemicals or heat, or be caused by a disease called aniridia. It leads to scarring and severe vision loss in both eyes as well as chronic pain and redness. The project, published in STEM CELLS Translational Medicine was funded by UK Stem Cell Foundation, Scottish Enterprise and the Chief Scientist Office, part of Scottish Government Health Directorates.