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Professor Andrew McIntosh (Centre for Clinical Brain Sciences), Professor Ian Deary (Centre for Cognitive Ageing and Epidemiology), Dr Michelle Luciano (Centre for Cognitive Ageing and Epidemiology) and colleagues (University of Edinburgh and King's College London) have published results from a study suggesting that people affected by depression may have genes associated with anxiety, worry and low mood. The DNA of over 300,000 people was analysed and many genes were found to link to neuroticism – characterised by feelings of anxiety, worry and guilt. The genes are also linked to depression. The findings help shed light on the causes of depression – which affects one in five people – and could provide information to help better diagnosis and treatment for individuals, scientists say.