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Dr Heather Whalley and Prof Andrew McIntosh (both Centre for Clinical Brain Sciences) and colleagues from the Centre for Cognitive Ageing & Cognitive Epidemiology and the University of Glasgow have found, using diffusion tensor imaging, that white matter integrity is reduced in people with symptoms indicative of depression compared to those without.
Congratulations to Dr David Howard, Professor Andrew McIntosh (both Centre for Clincial Brain Sciences) and colleagues, who have identified nearly 80 genes that may be involved in depression.
Researchers at the University of Edinburgh (Division of Psychiatry, Centre for Cognitive Ageing and Cognitive Epidemiology, Institute for Genetics and Molecular Medicine and brain imaging facilities) along with the universities of Aberdeen and Dundee, are involved in The Stratifying Resilience and Depression Longitudinally (STRADL) study. More than 600 volunteers have already been recruited for this £4.7m study (funded by the Wellcome Trust) and the study is continuing to recruit.
A major fund has been established to support pioneering research into mental health and early death in people with epilepsy. The Juliet Bergqvist Memorial Fund has been made possible by a generous gift from a family affected by epilepsy and suicide. Researchers at the University of Edinburgh are using anonymised health data to link a diagnosis of epilepsy to diagnoses for mental health conditions and causes of death.
Prof Andrew McIntosh (Centre for Clinical Brain Sciences - Psychiatry), Prof David Porteous (Inst
Dr Christos Gkogkas and colleagues (Centre for Discovery Brain Sciences, and Patrick Wild Centre) have published a study that may shed light on why a certain category of antidepressant drugs stop working in some people.
Hundreds of genes have been linked to depression in a study involving data from more than two million people that sheds light on why some people are more likely to develop the condition than others. Researchers led by Professor Andrew McIntosh at the Centre for Clinical Brain Science are now inviting people in Scotland to take part in a study known as The Genetic Links to Anxiety and Depression (GLAD) Study to understand more about the role of DNA in common mental health conditions.
Professor Andrew McIntosh (Centre for Clinical Brain Sciences), Professor Ian Deary (Centre for Cognitive Ageing and Epidemiology), Dr Michelle Luciano (Centre for Cognitive Ageing and Epidemiology) and colleagues (University of Edinburgh and King's College London) have published results from a study suggesting that people affected by depression may have genes associated with anxiety, worry and low mood. The DNA of over 300,000 people was analysed and many genes were found to link to neuroticism – characterised by feelings of anxiety, worry and guilt. The genes are also linked to depression. The findings help shed light on the causes of depression – which affects one in five people – and could provide information to help better diagnosis and treatment for individuals, scientists say.
Prof Andrew McIntosh (Centre for Clinical Brain Sciences - Psychiatry) and colleagues have publis
Dr Stella Chan (Clinical Psychology) has been awarded the British Psychological Society Public Engagement and Media Award for 2017.