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Research led by Dr Martha Koerner (School of Biological Sciences) has resulted in fresh insights into the rare genetic disorder known as MeCP2 duplication syndrome, which mainly affects boys and leads to severe intellectual disability, seizures and impaired motor function, that could pave the way for new treatments for the condition.
Dr Matthew Lyst, Prof Adrian Bird and colleagues (School of Biological Sciences) have published a study that examines the structure and interactions of proteins whose genes are mutated in Rett Syndrome, a disease that results in intellectual disability in girls.
Professor Giles Hardingham (Centre for Integrative Physiology and Associate Director for the new UK Dementia Research Institute at University of Edinburgh) and colleagues have published a study that uncovers how neurones influence astocyte function.
Prof. Mike Cousin (Centre for Integrative Physiology and Muir Maxwell Epilepsy Centre) has been awarded an Investigator Award in Science by the Wellcome Trust.
Congratulations to Dr Tom Wishart (Roslin Institute) and colleagues on their recent article successes! The 2016 paper (Quantitative imaging of tissue sections using infrared scanning technology) was awarded 'Runner-Up' in the Journal of Anatomy's Best Paper Prizes 2016, and the 2013 article (Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting) is among the top 10% most cited PLOS ONE articles. Well done to Tom and his colleagues!
Professor Mike Ludwig (Centre for Integrative Physiology) has found a new group of retinal cells
Applications are invited for four 3.5 year full-time fully funded PhD studentships spanning basic and translational brain sciences in the biological mechanisms underlying autism.
Dr David Hay, Dr Baltasar Lucendo-Villarin, Jose Meseguer-Ripolles and Dr Kate Cameron (all MRC Centre for Regenerative Medicine, University of Edinburgh), in collaboration with the Universities of Aberdeen and Glasgow, have developed a stem cell technique to assess the effects of maternal cigarette smoking on the developing foetus. Their findings reveal that the potent cocktail of chemicals in cigarettes is particularly harmful to developing liver cells and affects male and female foetuses differently.
Dr Thomas Becker and colleagues in the Centre for Neuroregeneration have used the regenerative capacity of zebrafish to uncover key mechanisms in the regrowth of spinal cord neurones following damage.They found that collagen 12 is produced by fibroblasts and this changes the structure of the support matrix which surrounds the nerve fibres, enabling regrowth across the wound site.