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The Centre for Clinical Brain Sciences (CCBS) was profiled in The Lancet, in an article outlining the structure and research focus of the Centre.
Professors Joanna Wardlaw (Centre for Clinical Brain Sciences, University of Edinburgh), Karen Horsburgh (Centre for Neuroregeneration, University of Edinburgh) and Rhian Touyz (Institute of Cardiovascular & Medical Sciences, University of Glasgow) are guest editors on the recently released Clinical Science special edition on small vessels, dementia & chronic disease.
Congratulations to Prof Seth Grant (Centre for Clinical Brain Sciences) and his research group, who have been awarded a grant of £1.3m by the Wellcome Trust to map the human brain. The project is built upon their previous work creating another such map - called a synaptome - for the mouse brain. The researchers hope to map the trillions of connections between brain cells, potentially revealing new insights into the foundations of behaviour and brain disease.
The pioneering dementia ‘buddy scheme’ headed by Dr Chris Henstridge (Centre for Discovery Brain Sciences) and co-ordinated by Lilian Kennedy (Social Anthropology) was recently featured on BBC News. The scheme pairs university researchers with people who are living with dementia to enable them to learn from each other.
Prof Tara Spires-Jones (Centre for Discovery Brain Sciences) and colleagues have published a study investigating Alzheimer's, showing that a protein called clusterin builds up in vital parts of neurons, synapses, and may damage these links.
Professor Tara Spires-Jones (Centre for Discovery Brain Sciences) has co-led a study that has demonstrated the presence of phosphorylated α-synuclein at synapses, and disrupted synaptic function, in brain tissue from patients with a common form of dementia, Dementia with Lewy Bodies.
A dementia ward at the Royal Edinburgh Hospital has been given a makeover as part of a project funded by a University of Edinburgh Innovation Initiative Grant that explores how colour can improve the daily experience of patients, visitors and staff. This collaboration between Edinburgh College of Art and ArtLink, staff at the Royal Edinburgh Hospital, and patients' relatives has helped to create a calmer environment according to hospital staff.
Dr Heather Whalley and Prof Andrew McIntosh (both Centre for Clinical Brain Sciences) and colleagues from the Centre for Cognitive Ageing & Cognitive Epidemiology and the University of Glasgow have found, using diffusion tensor imaging, that white matter integrity is reduced in people with symptoms indicative of depression compared to those without.
Congratulations to Dr David Howard, Professor Andrew McIntosh (both Centre for Clincial Brain Sciences) and colleagues, who have identified nearly 80 genes that may be involved in depression.
Dr Christos Gkogkas and colleagues in the Patrick Wild Centre have found that a commonly used diabetes drug, Metformin, could help people with a common inherited form of autism (fragile X syndrome).