Ophthalmic Imager and Analyst
The Edinburgh Clinical Research Facility wishes to recruit an enthusiastic, independent person to provide technical support to a growing programme of research featuring ophthalmic imaging and analysis to study diseases of the eye, brain and body. Located at the Edinburgh BioQuarter, Royal Infirmary campus, the role will principally involve conducting eye imaging assessments, communicating with participants and liaising with various study teams. The main responsibilities of the post-holder is to schedule study visits, undertake protocol-based ophthalmological imaging of participants, assist in the analysis of images, and follow quality assurance procedures to ensure that all data is accurately recorded.
Vacancy ref: 048670, Deadline: 8 August 2019
Postdoc Research Fellow - molecular mechanisms underlining autism spectrum disorders
A Post-Doctoral level position is available for an ambitious and talented scientist to study molecular mechanisms underlining autism spectrum disorders (ASDs) and intellectual disabilities (IDs). SynGAP1 is a Synaptic GTPase Activating Protein, one of the most abundant components of the postsynaptic density, and plays critical roles to control synaptic plasticity and various behaviours. SynGAP1 mutations have been found in ASD and ID patients at unusually high frequency but a precise mechanism that causes these symptoms is not yet understood. The aim is to evaluate and develop potential therapeutic strategies we are going to study the nature of a SynGAP1 missense mutation found in a human patient. The applicant must have extensive experience in molecular biology, cell biology (including use of primary neuronal cultures), biochemistry and florescent imaging along with a strong interest in the fundamental molecular mechanisms underlining these brain disorders. Experiences in production and phenotypic analysis of genetically modified mice and/or in use of CRISPR/Cas 9 genome editing systems will be advantageous.
Vacancy ref: 048743, Deadline: 22 August 2019
Research technician - preclinical PET/CT imaging
A research technician position is available for an enthusiastic and dynamic individual to join the research and development (R&D) team working on preclinical PET/CT imaging at the University of Edinburgh. This post aims to support small animal research ongoing within the Tavares group, as part of continuing efforts to develop new PET imaging probes. We are looking for someone with experience in non-surgical and surgical in vivo procedures in rodents as well as competence in handling of rodents, administration of substances, withdraw of fluids, tissue sampling, weighing, scoring and experimental monitoring. Expertise in basic laboratory procedures, experience in laboratory technical support and outstanding organizational skills are key to this post.
Vacancy ref: 047793, Deadline: 23 August 2019